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We developed a GLP-1 analog supaglutide by fusing a pair of GLP-1 molecules with immunoglobulin constant region that contains partial hinge chains ( Kumar et al., 2007 Wang et al., 2010). In order to prolong the action of GLP-1, great efforts have been made in the past decade and two strategies are accessible: one is the use of DPP-IV inhibitors and the other is the development of DPPIV-resistant analog through structural modifications which prevent DPP-IV degradation ( Drucker et al., 2010, 2011 Lindamood and Taylor, 2015 Lee, 2016 Rajeev and Wilding, 2016). However, native GLP-1 is not suitable for therapeutic use due to its short-circulating half-life ( t1/2 < 2 min), which results mainly from rapid enzymatic inactivation by dipeptidyl peptidase-IV (DPP-IV), and/or rapid kidney clearance ( Kieffer et al., 1995). The physiological properties of GLP-1 render it as an ideal therapy for obesity and type 2 diabetes (T2D) ( Rajeev and Wilding, 2016). It exerts numerous biological functions including stimulating glucose-dependent insulin secretion, inhibiting glucagon release, inducing satiety and slowing gastric emptying ( Rajeev and Wilding, 2016). Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted by gastrointestinal L cells in response to nutrient ingestion Meier and Nauck (2005). Our findings suggest that supaglutide exerts beneficial effect on established obesity through reducing energy intake and is associated with brown remodeling of white adipose tissue. Furthermore, supaglutide improved glucose tolerance, and insulin sensitivity in the obese mice suggesting improved glucose and energy homeostasis. This is consistent with the observation that supaglutide increased tolerance of the mice to cold environment associated with up-regulation of Ucp1 in the inguinal fat. Remarkably, supaglutide reduced hepatic lipid accumulation and altered morphometry in favor of small adipocytes in fat. Importantly, the intervention significantly reduced fatty liver, decreased liver triglyceride content, and concomitantly ameliorated liver injury exemplified by declined hepatic alanine aminotransferase (ALT) and aspartic transaminase (AST) content. Compared to the placebo control, supaglutide treatment improved lipid profile, i.e., significantly decreased circulating total cholesterol levels, declined serum triglyceride, and free fatty acid levels. We found that supaglutide treatment reduced body weight, which was associated with reduced food intake. Expression of uncoupling protein 1(Ucp1) in adipose tissues was evaluated by Western blotting. Liver and adipose tissues were collected for histology analysis. Glucose tolerance and insulin resistance were evaluated by intraperitoneal glucose tolerance test and insulin tolerance tests. Cold tolerance test was performed to evaluate brown-adipose tissue (BAT) activities in response to cold challenge. Metabolic conditions were monitored and energy expenditure was assessed by indirect calorimetry (CLAMS). Mice were fed with high-fat diet (HFD) for 6 months to induce obesity and then subjected to supaglutide treatment (300 μg/kg, bi-weekly for 4 weeks), and placebo as control. Here, we investigated the effects of supaglutide in regulating energy homeostasis in obese mice. We demonstrated that this formulation possessed long-lasting GLP-1 actions and was effective in glycemic control in both type 1 and type 2 diabetes rodent models. We recently developed a novel GLP-1 mimetics (supaglutide) by genetically engineering recombinant fusion protein production techniques. However, the therapeutic use of native GLP-1 is limited due to its short half-life. GLP-1, an important incretin hormone plays an important role in the regulation of glucose homeostasis. 4Departments of Physiology and Medicine, Faculty of Medicine, University of Toronto, ON, Canada.3Division of Endocrinology and Metabolism, Keenan Research Centre for Biomedical Science, St.1Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China.Yun Wan 1 Xi Bao 2 Jiabao Huang 2 Xiangyu Zhang 2 Wenjuan Liu 1,3 Qiaoli Cui 1 Dongdong Jiang 1 Zhihong Wang 1 Rui Liu 1 Qinghua Wang 1,2,3,4 * Professor Rubeus Hagrid stated that they were "dead clever". Thestrals were social creatures who lived in herds. they're dead clever an' useful!" - Hagrid during a fifth year Care of Magical Creatures lesson Another distinction was their sharp fangs used to seize and slash their prey. These eerie horses had long black manes, as well as a large tail, either with flowing black hair, like horses or ending in a tuft, like zebras. This smooth and dark skin was a bit slippery and so thin that Thestral's bones were clearly defined through the entire extension of their sleek bodies. Their fleshless, lustrous bodies were covered with a translucent and glossy coat. Unlike the Abraxan, another breed of winged horses, Thestral's wings did not possess any feathers at all they had vast, black and leathery wings that were more similar to those of bats. Additionally, they were lured by the scent of blood, which was bad for their reputation.īeing a type of winged horse, most of their anatomy was identical to a horse, excluding their large wings that sprouted from their back. This was because they were seen as having big, bony figures and their dragon-like faces which bore white, glittering eyes that lacked both expression and pupils. Thestrals had quite a disturbing appearance and the wizards who were capable of seeing them often described these creatures as being sinister and spooky. Standing still and quiet in the gathering gloom, the creatures looked eerie and sinister." - Description Wings sprouted from each wither - vast, black leathery wings that looked as though they ought to belong to giant bats. Their heads were dragonish, and their pupil-less eyes white and staring. They were completely fleshless, their black coats clinging to their skeletons, of which every bone was visible. " If he had had to give them a name, he supposed he would have called them horses, though there was something reptilian about them, too. Ī Thestral was also one possible corporeal form of the Patronus Charm. Breeding as well as owning these beasts might be discouraged or even illegal without Ministry consent in fact, wizards that lived in areas not protected against Muggles were forced by law to perform Disillusionment Charms on their Thestrals regularly. ĭue to Thestrals' classification as XXXX, only experienced wizards should try to handle Thestrals. Thestrals were, undeservedly, known as omens of misfortune and aggression by many wizards because they were visible only to those who had witnessed death at least once. They were very rare, and were considered dangerous by the British Ministry of Magic. They were native to the British Isles and Ireland, though they had been spotted in parts of France and the Iberian Peninsula. The Thestral was a breed of winged horse with a skeletal body, a face with reptilian features, and wide, leathery wings that resembled a bat's. Now, thestrals -" - Rubeus Hagrid and Hermione Granger discussing Thestrals in a Care of Magical Creatures lesson Righ', now, who can tell me why some o' you can see them an' some can't? Go on then." Hermione Granger: " The only people who can see thestrals are people who have seen death." Rubeus Hagrid: " Tha's exactly right, ten points ter Gryffindor. Rubeus Hagrid: " Don' worry, it won' hurt yeh. Links to emulators and fan translation projects is allowed, but any posting of ROMs will be deleted. If you post something you didn't make, please give proper attribution to the original creator. Only post things that are related to Rhythm Heaven. No trolling, low-effort, or NSFW/NSFL content. Repeatedly posting similar or excessively common content is spam. Feel free to post fan art, music, remixes, games, pretty much anything Rhythm Heaven-related. To conclude, I want to list some things I wish the developers would've made instead of devoting resources to the prequel games.This is a subreddit completely based on the excellent Nintendo franchise Rhythm Heaven (Rhythm Tengoku in Japan, Rhythm Paradise in Europe, Rhythm World in South Korea). Do I mean Fillbots 2 from the DS, or do I mean Fillbots 2 from Megamix which is really Fillbots 1? For example, one of my favorite games is Fillbots 2. The prequel games also add unnecessary confusion when talking about some of the games. In the first act of the game, Donut Land and Songbird Land don't use prequel games, just some of the easier games from the GBA, DS, and Wii games. The prequel games aren't even a consistent part of the game. If they could do it for the new games, why couldn't they do it for the rest of the prequel games? However, the games which are brand new in Megamix (like Catchy Tune and First Contact) do have music that sounds like their sequels. The prequel games have music that sounds nothing like their future "sequels" that aren't really sequels, which really disconnects them from the original games they're based on. The sequels to normal games always have music that sounds like the original game, either the same song or a remix. Despite their intentions, I don't think it really worked to get new players into the series since Megamix sold worse than Fever, making the prequel games even more pointless.Īnother thing that really bothers me is the music to the prequel games. chrislo27 has made a new version of a free Rhythm Heaven custom remix editor, and as of now it’s quite worth looking into. But every month we have large bills and running ads is our only way to cover them. Game files extracted and decompiled using this tool can be used in conjunction with this patch. In-depth documentation for Tickflow can be found here. We dont have paywalls or sell mods - we never will. Tickompiler is a compiler/decompiler for Tickflow, a language based on the bytecode format used by the game Rhythm Heaven Megamix to describe its rhythm games. If they wanted to ease new players into the series, they should've just put more of the easier games in the first act, like Night Walk GBA, The Dazzles, or Double Date. Mods & Resources by the Rhythm Heaven Megamix (RHMM) Modding Community. Several of the games that got a prequel are easy enough in their original versions: Karate Man, The Clappy Trio, Sneaky Spirits, and Micro-Row. Megamix starts off with an easier version of the Karate Man game that introduced new players to the series back on the GBA. Now the main argument I see in support of them is that they're a way to get new players into the series. Check out the RH Modding Server as well!įor a game that does so much well, I think the prequel games, the easier versions of previous games in the series, are easily the worst part of the game.Come and join the /r/rhythmheaven Discord Server!.Please do not advertise your chat/project/whatever unless you have something to show for your work! This is a subreddit completely based on the excellent Nintendo franchise Rhythm Heaven (Rhythm Tengoku in Japan, Rhythm Paradise in Europe, Rhythm World in South Korea). Please Support the Official ReleaseSong: Lockstep Tutorial 1Composers: Tsunku & Yumi TakahashiGame: Rhythm Heaven MegamixConsole: 3DSFull Playlist: https:/. Moderator decisions are final, please respect the moderator team and their actions. All data updated to patch v0.12. Make sure to follow the guidelines outlined in the Reddiquette for a more pleasant experience. Find out the effectiveness of each ammo against a specific armor class. Recent News Official LinksĪs well as the above rules, the Reddit Content Policy is in place as well - please familiarize yourself with this. Please make sure to follow the rules noted below in the side bar. These are the armor penetration tables and ammo performance for each piece of armor and each ammo, showing the penetration chance and remaining armor of each hit done to armor by specific ammo. Search, sort, and filter to easily compare the different ammo types. As of this ammo chart is no longer up to date and will not be updated anymore. This is an unofficial, community-run subreddit. All Credit goes of course to NoFAM <3 Updated for Ammo changes 31/1/21 (M62. As always I prefer a photo version in landscape mode to have on my PC to look at. 300 (SIG MCX) 7.62x51mm (Hi Caliber) 7.62x54mm (Mosin/SVDS). Thanks to u/NoFoodAfterMidnight again for the supreme support and fast updates. Planned pages: Rigs & Backpacks, Barter Items, Hideout Upgrades & Crafting, Task Items, and more. Escape from Tarkov is a hardcore and realistic online first-person action RPG/Simulator with MMO features and a story-driven walkthrough currently in development by Battlestate Games. Compact 7.62x25mm (TT Pistol) 9x18mm (9mm Makarov) 9x19mm (9mm MP5) 9x21mm (SR-1MP). Pages available: Ammo (By NoFoodAfterMidnights), Armor & Helmets, Melee Weapons. When you are working with specialty papers, from Epson, Avery, etc., they enclose printer instructions which tell you which paper settings to use. Make sure to choose the correct “PAPER TYPE” setting. These settings are generally found under the advanced settings option. I always choose “BEST PHOTO”, even if I am not printing a photo (I find is best to treat the printable image as a photo). The majority of the time I use “BORDERLESS PRINTING” and make sure “SHRINK TO FIT” is NOT checked because I do not want the printer to shrink my image. This will vary based on the printer manufacturer. Make sure to adjust the printer settings on your printer. The most overlooked component of printing at home tends to come with the printer settings. These papers are commonly found in the scrapbooking sections of stores such as Michael’s and Hobby Lobby. I do not recommend this type of card stock as it is porous and can have a coating. The number one printing problem comes from customers who are trying to print onto CRAFT STORE card stock. I do not recommend printing on cover or heavyweight craft paper for candy bar wrappers. I personally use Epson 4 or 5 star photo paper because it seems to hold up the best with temperature change, the colors are bold and the label does not wrinkle when wrapped around the candy bar. Using a photo paper is especially important if your candy wrapper has a photo because photos will not appear sharp on non-photo paper. This is a non-glare matte photo paper, so if you are planning on photographing your candy bars, this one photographs beautifully. It prints beautifully, and it folds well over the candy bar. ALWAYS PRINT ONTO WHITE PAPER: Here is the Epson Matte Premium Printer Paper I recommend. If not, you can download Adobe reader for free here: or open the jpeg into a software program of your choice.Ģ. Open the PDF into the PDF viewer (this comes on most computers). DOWNLOAD YOUR PRINTABLES -The labels come in both jpeg and pdf.All you have to do is download, print, trim and wrap around the Hershey bar. When you order personalized printable wrappers through Baer Design Studio, all the editing is done for you. Candy Bar Wrappers make great party favors for birthdays, graduations, retirement parties, engagement parties, baby showers, etc. It is easy to learn how to make printable candy bar wrappers at home for the standard Hershey chocolate bars. How to make printable candy bar wrappers at home! Here are some of the most common ones: Medications There's a wide variety of things that can cause dilated pupils. Anisocoria is benign and affects about 20 percent of the population. But typically, dilated pupils don’t respond normally to light.Ī large pupil that is completely unresponsive to light is called a "fixed" dilated pupil.ĭilated pupils aren't the same as anisocoria, which is a common condition where both pupils react normally to light but differ in size by about a half millimeter or more. To some degree, pupil size tends to get smaller with age.Ī dilated pupil sometimes can still react to light - that is, get smaller in bright light or when a light is shined at the eye. Generally, normal pupils range in size from 2.0 to 4.0 millimeters (mm) in bright light, and 4.0 to 8.0 mm in the dark. In dim lighting, your pupils dilate (get larger) to allow more light in. In bright light, your pupils constrict (get smaller) to prevent too much light from entering your eyes. The size of your pupils is controlled by muscles in the colored part of your eye (iris ) and the amount of light reaching your eyes. With a dilated eye exam, your optometrist can identify early signs of an eye condition or disease.Ī dilated pupil allows your eye doctor to easily view and examine all the internal parts of your eye, including the retina, optic nerve and lens.Dilated pupils are pupils that are larger than normal in size. In fact, it may even affect your vision and prevent an accurate reading of your eyes. Pupil dilation is generally not necessary to obtain an accurate optical prescription. These imaging techniques provide the vital information your eye doctor needs to ensure your eyes are healthy. Thanks to advanced medical technology, digital retinal imaging and OCT devices are now widely used in place of pupil dilation. Q4: Which conditions can be diagnosed with pupil dilation?Ī dilated eye exam can facilitate early detection of many different eye conditions - even before symptoms appear.Įarly detection of these conditions is essential to preserving your vision, as vision loss often occurs before symptoms are noticed.Ī dilated eye exam can also identify possible signs of high blood pressure and other vascular conditions. Some people complain of headaches or general fatigue for a few hours after the pupil dilation. Most eye doctors recommend bringing a pair of sunglasses to your appointment, as well as someone who can drive you home.Īfter the pupil dilation, the effects on your vision usually last for 4-6 hours, so it is usually recommended not to return to office afterwards, read or use a digital screen, During this time, you may experience headaches, fatigue and mild ocular discomfort. The effects of pupil dilation generally last for a couple of hours. Sensitivity to bright light and sunlight.Pupil dilation has a distinct effect on each individual - eyes that are lighter in color, such as green, blue or hazel, usually dilate faster than darker eyes.Īfter 15-30 minutes, you may notice the following symptoms that indicate complete dilation of the pupils: Q3: How will pupil dilation affect my vision? Schedule an appointment with an eye doctor near you for an annual eye exam or if you notice any changes in your vision. SEE RELATED: The Importance of Pupil Exams Sit back and try to relax, this sensation will pass in a couple of minutes as your eyes begin to dilate.Īn allergic reaction to dilating eye drops is rare, but inform your eye doctor if you experience any of the following symptoms: Upon insertion of the dilating eye drops, you may experience mild burning or stinging. In this way, your eye doctor can easily identify early signs of cataracts, glaucoma and macular degeneration, as well as other eye conditions and diseases. Pupil dilation facilitates a clear view of the internal parts of your eye, enabling a thorough examination of the lens, retina and optic nerve. Here are some of the most frequently asked questions about pupil dilation so you can know what to expect at your next eye exam. This gives your doctor a better view of all your inner ocular structures and enables an easier examination of the retina and optic nerve located in the back of your eye. It is surrounded by the colored iris, the muscular membrane responsible for controlling the amount of light that enters the eye.ĭuring an eye exam, your eye doctor may insert dilating eye drops into your eyes to widen your pupils. The pupil is the black circle in the center of your eye. Having your eyes dilated during an eye exam can reveal essential information about your general health and facilitate early detection of eye disease. Pupil dilation creates a clear view to the back of your eye. But excessive consumption can easily cause heavy sedation. It produces effects that are both functional and mentally stimulating when used in moderation. Lineage: Outlier Z F3 x Crinkled Cookies F2 Seeds: 3 Feminized seeds per pack Height: Up to 4 Feet Yield: 2-4 Ounces Harvest Time: 75-85 Days from Sprout. Golfball-sized buds climb their way up the branches, finishing with lovely little cola groupings at the top! Her resin production is great for making hash and can see high. Is a true F1 hybrid that responds incredibly well to topping and training, as the satellite branches can reach the same heights as the main cola. The fathers used in this line produced both resin coverage as well as the black/red leaf traits. Sometimes expressing earth and mint subtles notes from the Blue Microverse side of things. The Blue Sprayed Shoes Remix‘s flavour profile provides a candied sweet syrupy grape big league chew with some children’s Tylenol syrup notes & blueberry back notes. Night Owl Seeds Night Owl Seeds Mango Isle F2 NEW 50.00 Add to cart Night Owl Seeds Dessert Isle NEW Night Owl Seeds Spice Melange NEW Night. Unlock the potential of premium cannabis genetics with Night Owl Seeds by Night Owl Genetics. Which draws on this resin coverage from the Grape Stomper OG & Blue Magoo Bx2 ancestry. The branches themselves are typically laden with glorious trichomes as are her buds. They base their decisions regarding genetics mostly on medicinal cannabis values as well as vigor, yield, smell, taste, stability, and resistance and use several grow methods from indoor, outdoor, greenhouse, coco, soil, organic and synthetics. Is the remixed version of the original Blue Sprayed Shoes, so do yourself a favour and slip into these gems! Blue Sprayed Shoes Remix produces medium to large plants expressing heavy branching, vast bud sites, and insane resin production. Dynasty Genetics Seeds and Professor P have been providing fantastic medical marijuana strains (MMJ) for the last 15 years. Night Owl Seeds Blue Sprayed Shoes Remix (3 pack. Night Owl Seeds Blue Sprayed Shoes Remix (3 pack) Saturated (Pixel 2 only): See the most vivid colors.Adaptive (Pixel 3 & later): See the most vivid colors and keep color details.Boosted: See accurate colors with more vividness.New notifications: Check new notifications on your lock screen.Lift to check phone: View your notifications when you pick up your phone.Tap to check phone: View certain info when you tap your screen twice.Learn how to turn off your screen when you’re not using it. Always show time and info (All Pixel phones except Pixel 4): Check the time, and some other info, even when your screen is off.Learn how to change what's on your idle lock screen. Idle lock screen (Pixel 4 only): Have your phone screen turn on when you’re nearby, or stay on even when idle.It also offers product filtering, allowing customers to view products by brand, type, color, or size. Context allows mobile customers to easily search your store thanks to the predictive search feature you can display live search results and quick links for products and store pages. Now Playing: Quickly identify songs you hear near you. Why Context is the best Shopify theme for mobile customers.Double line clock: Choose whether a double-line or single-line clock displays on the lock screen.Show lockdown option: Learn more about lockdown.Lock screen message Add a line of text to your lock screen.Lock screen: Choose how notifications show on your lock screen.Set a screen saver to show photos, colorful backgrounds, and more while your phone is charging. Activate Google Assistant on your Pixel 8 and Pixel 8 Pro and ask, "How do I keep my phone unlocked longer?" Learn more about Pixel support on Assistant.Īutomatically adjust your screen's color temperature to the light around you.įor some content, you can automatically raise the refresh rate for: Tip: This increases battery usage.Screen attention works best when the screen is well-lit but not in direct sunlight.Keep your screen turned on when you're looking at it. Tap Dark theme.Ĭhange how long it takes for your phone’s screen to go black when you’re not using it. You can save battery by using a dark color scheme on some screens, like your Settings app. Learn how to change your wallpaper.Ĭhange supported app icons to match your phone's color scheme. Wallpaper (Pixel 1 only): Pick from default wallpapers, live wallpapers, and your photos.Learn how to change your styles & wallpapers. Styles & wallpapers (Pixel 2 & later): Change your phone's accent color, icon shapes, and fonts, or pick a type of wallpaper. Lott mistakenly states that I did not mention that one National Research Council committee member dissented from the committee’s conclusion that “it is not possible to determine that there is a causal link between the passage of right-to-carry laws and crime rates.” I did, in fact, state in my piece that the vote was not unanimous. My investigation involved far more than the impact of concealed-carry laws and ultimately concluded that more guns-period-are associated with more crime and violence. Lott’s inaccuracies certainly do not reflect the true weight of the evidence. One of them, for example, is a paper on the relationship between crime and subscriptions to Handguns magazine. drops after people are allowed to carry concealed handguns.” Included among these 24, which are listed on his Web site, are the irrelevant papers mentioned above, as well as other studies that do not show links between concealed carry policies and low crime. Lott is also wrong in his contention that I ignore 24 peer-reviewed publications “showing that crime in the U.S. Not only does Lott inflate the number of studies that support his thesis, but he also completely omits many peer-reviewed studies that belong on the other side. In total, one third of his pro–concealed-carry citations refer to his own work. Lott also includes the second edition of his own book as one of these 18 peer-reviewed studies. A second paper investigates how abortion relates to crime, a third concerns laws that prevent minors from owning guns-again, irrelevant to concealed carry. One is a paper by Lott on gun storage laws that has nothing to do with concealed carry. Many of these 18 supposed pro-carry studies are off-topic. In it he asserts that 18 peer-reviewed studies show right-to-carry laws reduce violent crime but only 11 suggest a different result.īut his two-thirds claim is false. He asserts “two thirds of the peer-reviewed, published literature shows that concealed carry laws help reduce crime.” This figure comes from a 2012 paper Lott himself wrote for the Maryland Law Review. If Moyer had even read the 1998 edition of More Guns, Less Crime, she would have learned this. Moyer has a long discussion of Arthur Kellermann’s work on the risks of guns in the home, and notes that Kellermann studied “444 people who had been killed between 19 at home.” But Moyer fails to note that, in fact, in only eight of these 444 homicide cases was the murder weapon a gun that had been kept in the home ( The New England Journal of Medicine, February 3, 1994, p. Take one example of Moyer’s sloppiness or bias in her article. The study also relies almost exclusively on trends in Hawaii to predict violent crime rates in Idaho, Minnesota, Mississippi, Nebraska and Utah. She references a recent unpublished paper by John Donohue, Abhay Aneja and Kyle Weber, but, unlike other studies, they don’t measure the number of permits issued, account for any other gun-control laws or deal with well-known statistical errors (such as truncation problems from a lot of zero values in the crime rates). drops after people are allowed to carry concealed handguns. Moyer quotes physician Garen Wintemute: “Few studies…suggest that liberalizing access to concealed firearms has, on balance, beneficial effects.” But Moyer ignores 24 peer-reviewed publications just showing that crime in the U.S. Finally, however, he pointed out the NRC’s own regressions consistently show right-to-carry laws reduce murder rates. Wilson, who had always supported gun control, had been on four previous panels but never had written a dissent. In the 10 years prior to the NRC report there were only two dissents out of 236 reports. Dissents in NRC reports are extremely rare. However, there was one unexpected dissent by preeminent criminologist James Q. As is typical of NRC reports, the 2005 “Firearms and Violence” by the council refrained from endorsing any of the over 100 different gun regulations it studied. The council was more supportive of right-to-carry laws than it was of any other gun law. Moyer cites the National Research Council (NRC), but fails to accurately describe its findings. Moyer appears completely unaware any of my research after 1998, making no mention of the 2nd and 3rd editions of More Guns, Less Crime (University of Chicago Press, 2000, 2010). I even provided Moyer with those published papers, but she doesn’t provide a single reference to or quote from them. About two thirds of the peer-reviewed, published literature shows concealed carry laws help reduce crime. Melinda Wenner Moyer’s article “Journey to Gunland” (October 2017) is very biased and ignores virtually all of the literature on right-to-carry laws and gun ownership since 1998. Lott, Jr., PhD, president of the Crime Prevention Research Center in Swarthmore, Pa., writes: |
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